<i>In vivo</i> CT imaging tracking of stem cells labeled with Au nanoparticles

Stem cell–based therapy offers great promise for a wide range of diseases and injuries that cannot be effectively treated by existing medicine therapies. However, the translation stem cell to clinic is still hampered lack profound understanding about survival, differentiation, migration, homing, fate transplanted cells during therapy. To address these issues, computed tomography (CT) based on nanomaterials, in particular gold nanoparticles (AuNPs), has been developed enhanced long-term imaging tracking cells. In this Mini-Review, we summarize recent progress AuNP-based CT cells, with focuses new strategies improve cellular uptake AuNPs better contrast, multimodal vivo. Finally, discuss challenges possible future developments regenerative other biomedical applications.